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Increased Birth-Defect Risk For Mothers Living Near Hazardous-Waste Landfills LONDON, ENGLAND -- Aug. 7, 1998 -- Women living within three kilometres of hazardous-waste landfills have a small, but significant increased risk of giving birth to children with birth defects, according to Dr. Helen Dolk and colleagues from London, England, in a study published in this week's issue of The Lancet. However, whether the increased risk detected by the study truly results from living near hazardous waste landfills or to other factors remains unknown, the researchers added. Dr. Dolk and colleagues focused on 21 hazardous waste landfills in Belgium, France, Denmark, Italy and the United Kingdom. By reviewing official birth-defect registries, they identified 1,089 children born with birth defects whose mothers had lived within 7 km of the landfills. They then matched each of these children with two children whose mothers also lived within 7 km of the landfills to see if there was a relation between the distance a mother lived from a landfill and the risk her child would be born with a birth defect. After accounting for differences in the mothers' age and socio-economic status -- factors previously linked to birth-defect risk -- the investigators found that there was a 33 percent increased risk of birth defects among children born of mothers living within 3 km of the landfills, compared with mothers living 3 to 7 km from the sites. "There was a significantly overall increased risk of neural-tube defects, malformations of the cardiac septa and malformations of the great arteries and veins in residents near the landfill sites in our study," the researchers write. Related Links: The Lancet E-mail this page to a friend or colleague! To print, use this version